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Best Antifungal Sprays (Over the Counter)

Written by Erin Porter

When I say I had a 30 year sinus infection, I am not exaggerating.  I would stop at nothing and would try anything to alleviate my sinus misery, I even tried not one sinus surgery but four.  I guess I was slow on the uptake when surgery one, two and three didn’t work, because I went back for a fourth.  That’s what you call desperation.  There were also decades of endless antibiotics, steroids, allergy shots, well, you know the drill.  If you are here reading this, you have probably been through it all yourself.   So why would I know what the best over the counter antifungal sprays are?  Because I have pretty much tried them all.

There are some great antifungals that can be found over the counter such as oil of oregano, silver (not the kind that is famous for turning people blue,) and antifungal sprays that are made from botanical oils that also include xylitol to help address biofilms and yeast.

Read on and I’ll give you the lowdown on each antifungal spray, what kills fungus in the sinuses, and a little background on the complications of allergic fungal sinusitis.  Also, see my television interview below for more information on my own battle with mold illness and fungal sinusitis.

What is Fungal Sinusitis & Why is it so Hard to Treat?

Fungal sinusitis, commonly referred to as allergic fungal sinusitis,  occurs when the mold spores are inhaled in our environment.  Many times this condition is chronic and difficult to treat as the inhaled spores then create an allergic reaction where thick fungal debris then blocks the sinus cavities.  Often time resulting in both a fungal and bacterial infection of the sinuses.

Often times allergic fungal sinusitis gets misdiagnosed or many people only get a partial diagnosis.  Let me explain.  For twenty years I was told I had a bacterial infection, so I chased that bacteria with every antibiotic under the sun.  Unfortunately, the infection kept returning while only growing stronger.  What was missed?  Nobody was culturing for fungus.

The Mayo Clinic was right.  Back in 1999, they released their findings and that was that almost all sinus infections were due to fungus.  Another unfortunate reality is that those same antibiotics that are needed to eradicate the bacteria feed the fungus.  There is also the issue of people not removing themselves or remediating the moldy environment they may be in.  Now you are beginning to see the complicated cycle.

CitriDrops Nasal Spray (nasal spray for fungal sinusitus)

bottle of citridrops nasal spray

CitriDrops were developed by an Ear, Nose and Throat physician who specializes in fungal sinusitis.  A physician who knows what kills fungus in the sinuses and set out to create a product to do just that!  He found many of his patients sometimes needed natural supplements for sinus infections either in addition to antibiotics or when fungus was the primary cause of their sinus infection.  Both Citridrops and bio active silver are good choices for a nasal spray for fungal sinusitis.  Discuss with your doctor.

This product includes xylitol which in studies has been shown to be effective on gram-negative bacteria and also has the ability to break up biofilms.  Citridrops are homeopathic, not habit forming and do not contain chemicals.

CitriDrops can be bought in a spay or in a bottle in which you can use for a dual purpose.  Not only can you add the drops to a NeilMed nasal irrigation bottle, but you can also use the drops to clean your fruits and vegetables with.  Micro Balance also carries many other mold products for your home, clothes, and nose.


  • Targets fungus and bacteria
  • ENT designed
  • Steroid and chemical free
  • Homeopathic
  • Non habit forming
  • Includes Xylitol to address biofilms and yeast


Below I discuss my battle with chronic fungal sinusitis (and other health issues) on televisions Know the Cause.

Bio-Active Silver Hydrosol

Sovereign Silver makes this silver antifungal spray.  With this silver, there is no risk of argyria (turning blue) and only has two ingredients.  They have a pharmaceutical version of this sinus spray as well called Argentyn 23.  You have to purchase it from a medical profession.  I got mine from my naturopath doctor.  Although I see Amazon carries the brand, they do not carry the sinus spray.  Speak to your doctor about whether they carry it as most functional doctors do.


  • Drug Free
  • Been used for thousands of years
  • Contains only two ingredients – 99.999 % pure silver and pharmaceutical grade water
  • Thins mucus
  • Non toxic because it’s in it’s purest form *says the company
  • No risk of argyria (turning blue)

Oil of Oregano Nasal Spray

Bottle of sinuorega oil of oregano sinus spray

Made by North American Herb and Spice, SinuOrega is a powerful antifungal!  The full ingredient list is Spring water, wild oregano oil, sea salt, clove bud oil, sage oil, and bay leaf oil.  Now that is a antimicrobial powerhouse!


  • No chemicals or synthetic additives
  • Non gmo
  • Alcohol free
  • Non addictive
  • Free of pesticides

Learn more about Fungal Sinusitis

Something to ask yourself is why you may need these antifungal nasal sprays in the first place.  We breathe in air more than we do anything else.  If our air quality is poor with too many toxic mold spores in the air we have a problem that antifungal sprays alone will not fix.  You must find the source of the mold you are inhaling and testing your home is not as complicated as it may seem.  I have created a simple video to walk you through a mold check of your home.

It’s also important to rotate your antifungals, as fungus is smart and can become accustomed to the same antifungal.  Doug Kaufmann, an expert in mycology (study of fungus and mold), suggests rotating them once per month.

For more safe and non toxic mold related products for your home, body, and nose, visit Microbalance Health Products.

Check out Eat Pray Get Well the book!  A Journey from Chronic Illness & Brokenness to Wholeness & Healing.  FOREWORD written by Doug Kaufmann.

Now also available on Amazon Kindle.

Disclosure:  I am not a physician.  Consult with your doctor before stating any new supplement for a sinus infection as they can be dangerous if left untreated.  In many cases a proper culture will need to be performed to find out which bacteria or fungus is growing in the sinuses.

This post contains affiliate links. I only mention very few products I actually use and can proudly stand behind. A small percentage

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Erin Porter
Erin Porter
I have been fortunate to be featured on national Television including PBS American Health Journal, Know the Cause, CTN, ABC, NBC, CBS and more. I was sick for decades, endured many surgeries, took over 100 courses of antibiotics, and then I changed everything and everything changed.

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About Erin

I have been fortunate to be featured on national Television including PBS American Health Journal, Know the Cause, CTN, ABC, NBC, CBS and more. I was sick for decades, endured many surgeries, took over 100 courses of antibiotics, and then I changed everything and everything changed. My book Eat Pray Get Well is about overcoming a tumultuous childhood, decades of chronic illness, and finding God in the process. Includes exclusive interviews with renowned Cardiologist Dr. Stephen Sinatra, Supermodel Carol Alt, Doug Kaufmann, and many more. Plus 55 gluten free recipes woven throughout. 

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